Title of article
Synthesis of the new ring system 2-oxo-[1,4]oxazino[3,2-e]indole, heteroanalogue of Angelicin
Author/Authors
Barraja، نويسنده , , Paola and Diana، نويسنده , , Patrizia and Montalbano، نويسنده , , Alessandra and Martorana، نويسنده , , Annamaria and Carbone، نويسنده , , Anna and Cirrincione، نويسنده , , Girolamo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
3
From page
4182
To page
4184
Abstract
A convenient synthesis of the 2-oxo-[1,4]oxazino[3,2-e]indole ring system, an heteroanalogue of Angelicin, is reported. Our synthetic approach consisted of the annelation of the oxazine ring on the indole moiety using 4-amino-5-hydroxy indoles as building blocks. The antiproliferative activity of the new compounds either in the dark or under UVA irradiation was investigated.
Keywords
1 , 4-Oxazinoindoles , 1 , Angelicin heteroanalogue , 4-Amino-5-hydroxy indoles , 4-benzoxazines
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1864974
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