Author/Authors :
Usachev، نويسنده , , Boris I. and Obydennov، نويسنده , , Dmitrii L. and Kodess، نويسنده , , Mikhail I. and Sosnovskikh، نويسنده , , Vyacheslav Ya.، نويسنده ,
Abstract :
6-(Trifluoromethyl)comanic acid reacts regioselectively with phenylhydrazine in water to give 5-[3,3,3-trifluoro-2-(phenylhydrazono)propyl]-1-phenyl-1H-pyrazole-3-carboxylic acid. Similar reaction in dioxane leads to 3-[3,3,3-trifluoro-2-(phenylhydrazono)propyl]-1-phenyl-1H-pyrazole-5-carboxylic acid. A strong solvent influence on the reaction route was also found for 6-(trifluoromethyl)comanic acid derivatives.
