Author/Authors :
Chang، نويسنده , , Chih-Wei and Chang، نويسنده , , Shih-Sheng and Chao، نويسنده , , Chin-Sheng and Mong، نويسنده , , Kwok-Kong T. Mong، نويسنده ,
Abstract :
A mild and efficient chlorination method for production of glycosyl chlorides is first described which employs inexpensive trichlorotriazine (TCT) and DMF as a chlorination reagent and is compatible with typical acid-labile hydroxyl protecting functions. The scope and limitations, reaction mechanism and its application in the sequential glycosylations are discussed.
