Title of article
Multicatalytic synthesis of 1,2-dihydroisoquinolin-1-ylphosphonates via a tandem four-component reaction
Author/Authors
Zhou، نويسنده , , Haibo and Jin، نويسنده , , Hanpeng and Ye، نويسنده , , Shengqing and He، نويسنده , , Xiaodan and Wu، نويسنده , , Jie، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
3
From page
4616
To page
4618
Abstract
A tandem four-component reaction of 2-bromobenzaldehyde, alkyne, amine, and diethyl phosphite catalyzed by the combination of palladium and copper salts provides a facile and efficient route to 1,2-dihydroisoquinolin-1-ylphosphonate. A cascade Sonogashira-intramolecular cyclization-nucleophilic addition may be involved in the reaction process.
Keywords
Diethyl phosphite , 1 , 2-Dihydroiso-quinolin-1-ylphosphonate , Four-component reaction , Multicatalysis , 2-Bromobenzaldehyde
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1865299
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