• Title of article

    Chemo-enzymatic asymmetric total synthesis of penienone

  • Author/Authors

    Mahapatra، نويسنده , , Tridib and Bhunya، نويسنده , , Rajib and Nanda، نويسنده , , Samik، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2009
  • Pages
    3
  • From page
    5392
  • To page
    5394
  • Abstract
    An asymmetric synthesis of penienone has been accomplished from (R)-5-hydroxymethyl-2-cyclohexenone by adopting a linear strategy. Lipase-PS-catalyzed enzymatic kinetic resolution (EKR) and Julia–Kocienski olefination followed by substrate-directed anionic hydroxymethylation have been successfully employed to achieve the target molecule.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2009
  • Journal title
    Tetrahedron Letters
  • Record number

    1865860