Title of article
Chemo-enzymatic asymmetric total synthesis of penienone
Author/Authors
Mahapatra، نويسنده , , Tridib and Bhunya، نويسنده , , Rajib and Nanda، نويسنده , , Samik، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
3
From page
5392
To page
5394
Abstract
An asymmetric synthesis of penienone has been accomplished from (R)-5-hydroxymethyl-2-cyclohexenone by adopting a linear strategy. Lipase-PS-catalyzed enzymatic kinetic resolution (EKR) and Julia–Kocienski olefination followed by substrate-directed anionic hydroxymethylation have been successfully employed to achieve the target molecule.
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1865860
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