Title of article
Selective arylation of 1,1-disubstituted olefins using a biphenyl-based phosphine in Heck coupling reactions
Author/Authors
Nadri، نويسنده , , Shirin and Joshaghani، نويسنده , , Mohammad A. Rafiee، نويسنده , , Ezzat، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
4
From page
5470
To page
5473
Abstract
The biphenyl-based phosphine, 2-diphenylphosphino-2′-methylbiphenyl is an effective ligand for palladium-catalyzed terminal arylation of 1,1-disubstituted olefins with aryl bromides in DMF and K2CO3 as base. The yields of products are independent of the electronic properties of the aryl bromides, however, the nature of the olefin has a major effect.
Keywords
C–C coupling , Heck reaction , 1 , 1-Disubstituted olefins , Biphenyl-based phosphine
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1865917
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