Synthesis of (+)-striatene: confirmation of its stereostructure

The first enantioselective synthesis of natural striatene (+)-1, isolated from liverwort Ptychanthus striatus, starting from commercially available (R)-Pulegone is described. Its stereostructure was confirmed by X-ray analysis of a 3,5-dinitrobenzoate derivative obtained from a key intermediate and its high optical purity was verified by chiral HPLC.