Title of article
Optimized synthesis of [3-15N]-labeled uridine phosphoramidites
Author/Authors
Baral، نويسنده , , Bharat and Kumar، نويسنده , , Pawan and Anderson، نويسنده , , Brooke A. and طstergaard، نويسنده , , Michael E. and Sharma، نويسنده , , Pawan K. and Hrdlicka، نويسنده , , Patrick J.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
3
From page
5850
To page
5852
Abstract
A short and high-yielding synthetic route to [3-15N]-labeled uridine phosphoramidite 1 (26% overall yield from uridine) has been developed. This will enable automated synthesis of isotopically labeled RNA strands and facilitate their use in structural studies.
Keywords
Phosphoramidite , Ribonucleotides , Isotope labels , NMR , nucleoside
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1866184
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