Title of article :
Stereoselective total synthesis of (−)-pyrenophorol
Author/Authors :
Yadav، نويسنده , , J.S and Subba Reddy، نويسنده , , U.V. and Subba Reddy، نويسنده , , B.V.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
An efficient stereoselective total synthesis of (−)-pyrenophorol 1 is described. The key steps involved in this synthesis are hydrolytic kinetic resolution (HKR), MacMillan α-hydroxylation, Horner–Wadsworth–Emmons (HWE) reaction, and Mitsunobu cyclization.
Keywords :
macrodiolide , Pyrenophorol , Hydrolytic kinetic resolution (HKR) , MacMillan ?-hydroxylation , Horner–Wadsworth–Emmons reaction , Mitsunobu cyclization
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
