Title of article
Iron chloride enhancement of dimethylzinc-mediated radical conjugate addition of ethers and an amine to alkylidenemalonates
Author/Authors
Yamada، نويسنده , , Ken-ichi and Maekawa، نويسنده , , Masaru and Yamamoto، نويسنده , , Yasutomo and Nakano، نويسنده , , Mayu and Akindele، نويسنده , , Tito and Tomioka، نويسنده , , Kiyoshi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
4
From page
6040
To page
6043
Abstract
The addition of FeCl3 and the use of DMSO as a solvent enabled the radical conjugate addition of a cyclic acetal and a cyclic amine to alkylidenemalonates using a reagent amount (12.5 equiv) of the radical precursors to give Michael addition products in up to 84% yield. This represents a great improvement over the 5% yield obtained under the previously reported conditions.
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1866322
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