Author/Authors :
Yamada، نويسنده , , Ken-ichi and Maekawa، نويسنده , , Masaru and Yamamoto، نويسنده , , Yasutomo and Nakano، نويسنده , , Mayu and Akindele، نويسنده , , Tito and Tomioka، نويسنده , , Kiyoshi، نويسنده ,
Abstract :
The addition of FeCl3 and the use of DMSO as a solvent enabled the radical conjugate addition of a cyclic acetal and a cyclic amine to alkylidenemalonates using a reagent amount (12.5 equiv) of the radical precursors to give Michael addition products in up to 84% yield. This represents a great improvement over the 5% yield obtained under the previously reported conditions.
