Title of article :
A facile one-step synthesis of 5-chloro-imidazo[1,5-a]quinazoline by microwave irradiation
Author/Authors :
Li، نويسنده , , Guo and Kakarla، نويسنده , , Ramesh and Gerritz، نويسنده , , Samuel W. and Pendri، نويسنده , , Annapurna and Ma، نويسنده , , Baoqing، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
A new and facile method has been developed for the one-step synthesis of 5-chloro-imidazo[1,5-a]quinazoline by cyclization of N-acylanthranilic acid A with 2-amino acetamide B1 or 2-amino-acetonitrile B2 in the presence of POCl3 under microwave irradiation. 5-chloro-imidazo[1,5-a]quinazolines can be further functionalized by displacement of 5-Cl group.
Keywords :
microwave , 4-Quinazolinone , Imidazoquinazoline
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
