Title of article :
Allyl tetrahydropyranyl ether: a versatile alcohol/thiol protecting reagent
Author/Authors :
Kumar، نويسنده , , Brijesh and Aga، نويسنده , , Mushtaq A. and Mukherjee، نويسنده , , Debaraj and Chimni، نويسنده , , Swapandeep S. and Taneja، نويسنده , , Subhash C.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
Allyl tetrahydropyranyl ether (ATHPE) can be used as a versatile protecting reagent. In combination with NBS/I2, O-allyl group can easily be replaced by hydroxyls (including tertiary-OH) or thiols, in the molecules comprising other reactive functional groups such as halogen, nitro, acetonide and alkene under mild reaction conditions (near neutral pH and ambient temperature).
Keywords :
Allyl tetrahydropyranyl ether , NBS , I2 , Lewis acid , alcohol , thiol
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
