Author/Authors :
Weymouth-Wilson، نويسنده , , Alexander C. and Clarkson، نويسنده , , Robert A. and Jones، نويسنده , , Nigel A. and Best، نويسنده , , Daniel and Wilson، نويسنده , , Francis X. and Pino-Gonzلlez، نويسنده , , Maria-Soledad and Fleet، نويسنده , , George W.J.، نويسنده ,
Abstract :
1,2-O-Isopropylidene-α-l-glucurono-3,6-lactone may be synthesized on a 100–200 g scale from cheaply available d-glucoheptonolactone in an overall yield of 94% in four steps via l-glucuronolactone. Subsequent elaboration to l-glucose, diacetone-l-glucose (1,2:5,6-di-O-isopropylidene-α-l-glucofuranose), and monoacetone-l-glucose (1,2-O-isopropylidene-α-l-glucofuranose) allows easy access to a range of l-sugar chirons.