Title of article
Asymmetric synthesis of oxindoles containing a quaternary stereogenic centre by catalytic O/C-carboxyl rearrangement
Author/Authors
Ismail ، نويسنده , , Muhammad and Nguyen، نويسنده , , Huy V. and Ilyashenko، نويسنده , , Gennadiy and Motevalli، نويسنده , , Majid and Richards، نويسنده , , Christopher J.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
3
From page
6332
To page
6334
Abstract
A catalysed O/C-carboxyl rearrangement generates the all-carbon stereogenic centre in phenyl 1,3-dimethyl-5-methoxy-2-oxoindoline-3-carboxylate (up to 57% ee). Crystallisation and removal of racemic crystals enhance the ee to 95%. The X-ray crystal structure of the cobalt metallocene–pyrrolidinopyridine nucleophilic catalyst employed is reported.
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1866520
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