Title of article :
A formal synthesis to (+)-nephrosteranic acid from chiral nitroalkyl derivatives
Author/Authors :
Barreto Jr.، نويسنده , , Cleber B. and Pereira، نويسنده , , Vera L. Patrocinio، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
A concise and versatile formal synthesis to (+)-nephrosteranic acid was accomplished from a common nitroderivative 2 in a sequence of six steps. The adduct 2 was obtained via a highly syn-diastereoselective conjugate addition of 1-dodecyl nitronate ion to chiral enoate Z-5 (yield = 80%; de = 95%), derived from d-(+)-mannitol.
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
