Title of article
A short synthesis of 3,6-disubstituted N-2-thienyl/aryl-indoles
Author/Authors
Borate، نويسنده , , Hanumant B. and Sawargave، نويسنده , , Sangmeshwer P. and Maujan، نويسنده , , Suleman R. and Sawargave، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
5
From page
6562
To page
6566
Abstract
A short synthetic strategy for 3,6-disubstituted-N-2-thienyl/aryl-indoles, involving reaction of substituted 2,4-difluoro/dichloro-styrene epoxide with substituted 2-formylaminothiophenes or substituted N-formylanilines in the presence of a base followed by treatment with an acid, has been developed. The method was applied for the synthesis of a number of indoles with a variety of substituents at 1, 3, and 6 positions of the indole moiety.
Keywords
Formylaminothiophene , Gewald synthesis , Styrene epoxide , indole
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1866688
Link To Document