Title of article
Highly diastereoselective allylation of lactols and their ethers using molecular iodine
Author/Authors
Yadav، نويسنده , , J.S. and Reddy، نويسنده , , B.V. Subba and Reddy، نويسنده , , A. Srinivas and Reddy، نويسنده , , Ch. Suresh and Raju، نويسنده , , S. Satyanarayana، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
4
From page
6631
To page
6634
Abstract
Lactols and their ethers undergo smooth allylation with allyltrimethylsilane in the presence of 5 mol % iodine in dichloromethane at −78 °C to afford C-allylfuranosides in good yields and with high diastereoselectivity. The use of iodine makes this method simple, convenient and practical. This is the first report on the allylation of lactols with allyltrimethylsilane using molecular iodine as a catalyst. Enhanced diastereoselectivity is the key feature of this protocol.
Keywords
Lactols , C-Allylfuranosides , allylation , iodine
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1866733
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