Title of article :
Regioselectivity in 2-X-pyrazine aminations by O-mesitylenesulfonylhydroxylamine
Author/Authors :
Borodkin، نويسنده , , Gennady I. and Vorob’ev، نويسنده , , Aleksey Yu. and Shakirov، نويسنده , , Makhmut M. and Shubin، نويسنده , , Vyacheslav G.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
The regioselectivity of 2-X-pyrazine aminations by O-mesitylenesulfonylhydroxylamine was studied experimentally and the results are discussed from the viewpoint of electronic and steric factors. DFT calculations are consistent with the reaction proceeding according to an SN2 mechanism.
Keywords :
N-Amine salts , linear free energy relationship , Mechanism , Selectivity , DFT calculations , amination , azines
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
