Title of article
A regioselective approach toward the synthesis of pharmacologically important quinone-containing heterocyclic systems
Author/Authors
Castellano، نويسنده , , Sabrina and Santoriello، نويسنده , , Marisabella and Campiglia، نويسنده , , Pietro and Cardillo، نويسنده , , Giovanna and Bertamino، نويسنده , , Alessia and Gomez-Monterrey، نويسنده , , Isabel and Novellino، نويسنده , , Ettore and Sbardella، نويسنده , , Gianluca، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
3
From page
6869
To page
6871
Abstract
An inexpensive and regioselective approach to dihydrothieno[3,2-g]quinoline-4,9-dione is reported. A combination of a mild version of Skraup reaction with a sequential substitution/Michael addition allowed the selective preparation in acceptable yield of a pharmacologically important quinone derivative, previously obtained only in trace and together with the other regioisomer.
Keywords
Skraup reaction , Michael addition , Quinone-containing antitumoral drugs
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1866917
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