Title of article
New route synthesis of indolizines via 1,3-dipolar cycloaddition of pyridiniums and alkynes
Author/Authors
Shang، نويسنده , , Yongjia and Zhang، نويسنده , , Min and Yu، نويسنده , , Shuyan and Ju، نويسنده , , Kai and Wang، نويسنده , , Cuie and He، نويسنده , , Xinwei، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
4
From page
6981
To page
6984
Abstract
A convenient synthesis of 2,3-di and 1,2,3-trisubstituted indolizines has been achieved via a 1,3-dipolar cycloaddition of pyridiniums and alkynes. Various alkynes and diynes were used instead of dimethyl acetylenedicarboxylate (DMAD) and its analogues in the traditional method. The corresponding 1,2,3-trisubstituted indolizines are useful building blocks for the construction of complex indolizine derivatives.
Keywords
Indolizine , 1 , 3-dipolar cycloaddition , Bridgehead N-heterocycles , alkyne , Diyne
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1866995
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