Title of article
Microwave-assisted synthesis of sodium sulfonates precursors of sulfonyl chlorides and fluorides
Author/Authors
Shakiru O. Alapafuja، نويسنده , , Shakiru O. and Nikas، نويسنده , , Spyros P. and Shukla، نويسنده , , Vidyanand G. and Papanastasiou، نويسنده , , Ioannis and Makriyannis، نويسنده , , Alexandros، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
4
From page
7028
To page
7031
Abstract
We describe the use of a microwave reaction for the conversion of various bromides to sodium sulfonates that have been further elaborated to sulfonyl chlorides. This new approach leads to much improved yields and shorter reaction times. Representative sulfonyl chlorides serve as precursors for the respective sulfonyl fluorides that are potent inhibitors of the fatty acid amide hydrolase.
Keywords
Sodium sulfonates , microwave , sulfonyl chlorides , Sulfonyl fluorides
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1867032
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