Title of article :
Enantiodivergent synthesis of (−)-methylenolactocin and (+)-methylenolactocin from d-mannitol
Author/Authors :
Ghosh، نويسنده , , Manju and Bose، نويسنده , , Sritama and Maity، نويسنده , , Soumitra and Ghosh، نويسنده , , Subrata، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
An enantiodivergent synthesis of both enantiomers of methylenolactocin is described through stereocontrolled addition of n-pentyl magnesium bromide to two d-mannitol-derived diastereomerically related aldehydes having an α-chiral center with a β hetero atom.
Keywords :
asymmetric synthesis , lactone , stereocontrol , anti-tumor compounds
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
