Author/Authors :
Mercey، نويسنده , , Guillaume and Brégeon، نويسنده , , Delphine and Baudequin، نويسنده , , Christine and Guillen، نويسنده , , Frédéric and Levillain، نويسنده , , Jocelyne and Gulea، نويسنده , , Mihaela and Plaquevent، نويسنده , , Jean-Christophe and Gaumont، نويسنده , , Annie-Claude، نويسنده ,
Abstract :
Mukaiyama aldol reaction between benzaldehyde and Danishefsky diene is promoted by ionic liquid-type salts. Hence, thiazolinium salts have been found to be the most efficient for this transformation. On a mechanistic point of view, only the Mukaiyama process is observed without any hetero Diels–Alder cycloaddition. In some cases, cyclisation of the Mukaiyama adduct occurred without addition of TFA. Interestingly, the thiazolinium catalyst can be recycled at least 10 times without loss of activity.
Keywords :
Mukaiyama reaction , Ionic liquids , Thiazolinium salt , Dihydropyranones
