Author/Authors :
Napolitano، نويسنده , , Carmela and Borriello، نويسنده , , Manuela and Cardullo، نويسنده , , Francesca and Donati، نويسنده , , Daniele and Paio، نويسنده , , Alfredo and Manfredini، نويسنده , , Stefano، نويسنده ,
Abstract :
The first synthesis of 6-phenyl-2,6-diazabicyclo[3.2.0]heptane 1 and its orthogonally protected precursor 2 is herein reported. Our strategy enables to chemically address the two nitrogen atoms of 2,6-diazabicyclo[3.2.0]heptane core individually and selectively, thus allowing rapid access to several subsets of widely substituted fused azetidines.