Title of article
Electrophilic fluorination: the aminopyridine dilemma
Author/Authors
Fields، نويسنده , , Stephen C. and Lo، نويسنده , , William C. and Brewster، نويسنده , , William K. and Lowe، نويسنده , , Christian T.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
79
To page
81
Abstract
An unusually high yielding fluorination of aminopyralid (3) using F-TEDA (SELECTFLUOR™) in warm water, followed by kinetic resolution (via iterative esterification/saponification) of the crude fluorination product with dry HCl in methanol produced pure ring-fluorinated pyridine 2 in an overall yield of 31% for the two steps.
Keywords
Electrophilic fluorination , Aminopyridine , F-TEDA
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1870473
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