Title of article :
An expeditious total synthesis of (±)-jamtine using condensation between imine and acid anhydride
Author/Authors :
Pérard-Viret، نويسنده , , Joelle and Souquet، نويسنده , , Florence and Manisse، نويسنده , , Marie-Line and Royer، نويسنده , , Jacques، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
A totally convergent and very short (three steps) synthesis of (±)-jamtine was described. The key step of this sequence was the condensation of 6,7-dimethoxy-3,4-dihydroisoquinoline and tetrahydrophthalic anhydride under microwave activation which occurred in good yield and high diastereomeric selectivity.
Keywords :
natural product synthesis , Pyrroloisoquinoline , Microwave-assisted synthesis , Imine condensation , Acid anhydride condensation , Jamtine , isoquinoline alkaloid
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
