Title of article
Enzymatic synthesis of (S)-glutaric acid monoesters aided by molecular docking
Author/Authors
Wang، نويسنده , , Bo and Liu، نويسنده , , Ji-Sheng Tang، نويسنده , , Xiaoling and Cheng، نويسنده , , Cheng and Gu، نويسنده , , Jiali and Dai، نويسنده , , Liyan and Yu، نويسنده , , Hongwei، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
309
To page
312
Abstract
An efficient enzymatic method for the synthesis of (S)-3-substituted glutaric acid monoesters which was aided by molecular docking has been described. The reaction was proceeded under mild conditions, and the desired products were afforded with up to 98% ee in the yield of 93%. The results demonstrate that molecular docking is efficient to facilitate selection of substrates in enzymatic reaction.
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1870635
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