Author/Authors :
Coleridge، نويسنده , , Brian M. and Bello، نويسنده , , Charles S. and Ellenberger، نويسنده , , David H. and Leitner، نويسنده , , Andreas، نويسنده ,
Abstract :
The efficient cross-coupling of 2-pyridylzinc bromide with functionalized aryl halides has been accomplished by a simple and highly efficient protocol. To the best of our knowledge, we report the first shelf life study of 2-pyridylzinc bromide which confirms the excellent stability of this compound and underlines the synthetic value of organozinc reagents in the cross-coupling reactions of sensitive heterocyclic nucleophiles on academic and commercial scale.
