Title of article
Critical importance of leaving group ‘softness’ in nucleophilic ring closure reactions of ambident anions to 1,2-diazetidines
Author/Authors
Brown، نويسنده , , Michael J. and Clarkson، نويسنده , , Guy J. and Fox، نويسنده , , David J. and Inglis، نويسنده , , Graham G. and Shipman، نويسنده , , Michael، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
382
To page
384
Abstract
Highly strained, four-membered 1,2-diazetidine rings are produced in good yields (50–98%) in nucleophilic ring closure reactions provided ‘soft’ leaving groups such as iodide are used, a finding that can be rationalised in terms of the Hard Soft Acids and Bases principle.
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1870686
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