Title of article
Asymmetric organocatalytic Michael-type reaction of phosphorus ylides to nitroolefins: synthesis of γ-nitro-β-aryl-α-methylene carboxylic esters
Author/Authors
Allu، نويسنده , , S. Suresh and Selvakumar، نويسنده , , Sermadurai and Singh، نويسنده , , Vinod K.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
446
To page
448
Abstract
We report, for the first time, asymmetric organocatalytic Michael-type addition of stabilized phosphorus ylides to nitroolefins mediated by bisthiourea catalyst. Its subsequent reaction with formaldehyde provides γ-nitro-α-methylene carboxylic esters in moderate to good yields and enantioselectivities (up to 63% ee).
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1870736
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