Title of article :
Synthesis of 3,5-diaryl-4-chlorophthalates by [4+2] cycloaddition of 1-ethoxy-2-chloro-1,3-bis(trimethylsilyloxy)-1,3-diene with dimethyl acetylenedicarboxylate and subsequent site-selective Suzuki–Miyaura reactions
Author/Authors :
Abid، نويسنده , , Obaid-Ur-Rahman and Ibad، نويسنده , , Muhammad Farooq and Nawaz، نويسنده , , Muhammad and Adeel، نويسنده , , Muhammad and Rama، نويسنده , , Nasim Hasan and Villinger، نويسنده , , Alexander and Langer، نويسنده , , Peter، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
The [4+2] cycloaddition of 1-ethoxy-2-chloro-1,3-bis(trimethylsilyloxy)-1,3-diene with dimethyl acetylenedicarboxylate (DMAD) afforded dimethyl 4-chloro-3,5-dihydroxyphthalate. Site-selective Suzuki–Miyaura reactions of its bis(triflate) provide a convenient approach to 3,5-diaryl-4-chlorophthalates containing two different aryl groups.
Keywords :
Silyl enol ethers , Suzuki–Miyaura reactions , Organochlorine compounds , Cyclocondensations
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
