Author/Authors :
Yadav، نويسنده , , J.S and Subba Reddy، نويسنده , , B.V. and Ramesh، نويسنده , , K. and Narayana Kumar، نويسنده , , G.G.K.S. and Grée، نويسنده , , René، نويسنده ,
Abstract :
Aldehyde, homoallylic amine and arene undergo smooth cyclization in the presence of BF3·OEt2 to afford 4-arylpiperidines in good yields and with high trans-selectivity. This is the first report on the preparation of 4-arylpiperidines via aza-Prins-Friedel–Crafts reaction.
Keywords :
Aza-Prins-Friedel–Crafts reaction , Homoallylic Amines , 4-Arylpiperidines , arenes
