Title of article
One-pot derivatization of medicinally important 9-aminoacridines by reductive amination and SNAr reaction
Author/Authors
Gellerman، نويسنده , , Gary and Gaisin، نويسنده , , Vladimir and Brider، نويسنده , , Tamara، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
836
To page
839
Abstract
A new highly efficient one-pot derivatization of medicinally important 9-aminoacridines (9-AA) at the amine position is described. Simple reductive amination and SNAr reaction using easily accessible starting materials give a fast entry to novel 9-AA derivatives for biological screening.
Keywords
9-aminoacridine , reductive alkylation , one-pot synthesis , nucleophilic substitution
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1870999
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