Title of article :
1,4-syn-Asymmetric induction in the titanium-mediated aldol reactions of chiral methyl α-silyloxy ketones
Author/Authors :
Lorente، نويسنده , , Adriana and Pellicena، نويسنده , , Miquel and Romea، نويسنده , , Pedro and Urpي، نويسنده , , Fèlix، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
Good levels of 1,4-syn asymmetric induction are obtained in the TiCl4-mediated aldol reaction of methyl α-silyloxy ketones with achiral aldehydes. Such methodology represents a new approach to the substrate-controlled acetate aldol reaction, which can be useful to design more efficient syntheses of natural products.
Keywords :
chiral ketones , titanium enolates , Stereoselective reactions , Acetate aldol reactions
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
