Title of article
Parallel synthesis enablement of 2-pyridyl-5-cyano-pyrimidine-6-ones—a novel class of HIF-hydroxylase inhibitors
Author/Authors
Chang، نويسنده , , Shang-Poa and Hungerford، نويسنده , , William M. and McDonald، نويسنده , , Wayne S. and Maguire، نويسنده , , Robert J. and Malony، نويسنده , , Kelly Q. and Subramanyam، نويسنده , , Chakrapani، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
952
To page
954
Abstract
The synthesis of various substituted 2-pyridyl-5-cyano-pyrimidine-6-ones was accomplished via a three-step protocol. The key aspects of this parallel protocol was the preparation of amidines from nitriles under mild conditions followed by cyclization with ethyl (ethoxymethylene)cyanoacetate.
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1871074
Link To Document