Title of article
A biomimetic approach to the synthesis of a mycolic acid motif
Author/Authors
Driver، نويسنده , , Cathryn H.S. and Balogun، نويسنده , , Mohammed O. and Toschi، نويسنده , , Gianna and Verschoor، نويسنده , , Jan A. and Baird، نويسنده , , Mark S. and Pilcher، نويسنده , , Lynne A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
2
From page
1185
To page
1186
Abstract
A new method for the stereoselective synthesis of the (R,R)-β-hydroxy-α-alkyl fatty acid fragment of mycolic acids, via an asymmetric anti-aldol reaction is reported. The ‘mycolic acid motif’ fragment was prepared in three steps and >98% ee.
Keywords
Tuberculosis , Mycolic acid , Mycolic acid motif , Asymmetric anti-aldol reaction
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1871253
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