Author/Authors :
Chinnam Naidu، نويسنده , , K. and Ravi Babu، نويسنده , , G. and Gangaiah، نويسنده , , L. and Mukkanti، نويسنده , , K. and Madhusudhan، نويسنده , , G.، نويسنده ,
Abstract :
We report facile and simple synthesis of a variety of 2-oxazolidinones from the corresponding halohydrins by reaction with KOCN in DMF catalyzed by DMAP. DMAP and temperature play key roles in enriching the yield of 2-oxazolidinones. A few examples in this Letter are applicable to pharmaceutically important processes.
Keywords :
Linezolid , Halohydrin , KOCN , DMAP , 2-Oxazolidinone
