Title of article
Boric acid catalyzed convenient synthesis of 2-amino-3,5-dicarbonitrile-6-thio-pyridines in aqueous media
Author/Authors
Shinde، نويسنده , , Pravin V. and Sonar، نويسنده , , Swapnil S. and Shingate، نويسنده , , Bapurao B. and Shingare، نويسنده , , Murlidhar S.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
1309
To page
1312
Abstract
A one-pot three-component condensation of an aldehyde, malononitrile, and thiophenol has been achieved by conventional and ultrasound method. The reaction has been catalyzed by boric acid in aqueous medium. This protocol afforded corresponding 2-amino-3,5-dicarbonitrile-6-thio-pyridines in shorter reaction times and high yields with the green aspects by avoiding toxic catalysts and solvents.
Keywords
aldehyde , Thiophenol , Boric acid , aqueous media , Ultrasonication , Malononitrile
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1871338
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