Title of article
Chemoselective addition of in situ prepared lithium alkynyl borates to aldehydes: a practical and transition metal free approach toward the synthesis of propargylic alcohols
Author/Authors
Francesco، نويسنده , , Irene Notar and Renier، نويسنده , , Antoine and Wagner، نويسنده , , Alain and Colobert، نويسنده , , Françoise، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
1386
To page
1389
Abstract
A convenient synthesis of functionalized propargylic alcohols arising from the 1,2-addition of lithium alkynyl-trimethyl borate onto aldehydes under transition metal free mild conditions is reported. The reaction tolerates a wide range of functional groups, is highly chemoselective and the propargylic alcohols are isolated in good to excellent yields.
Keywords
aldehyde , Lithium alkynyl borate , propargylic alcohol
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1871388
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