Title of article
A rapid and practical entry into cis-1,4-aminocyclohexanols
Author/Authors
Gallou، نويسنده , , Fabrice and Han، نويسنده , , Bo and Lu، نويسنده , , Jiang and Seeger-Weibel، نويسنده , , Manuela and Stoessel، نويسنده , , Anne-Florence and Allmendinger، نويسنده , , Simon، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
1419
To page
1422
Abstract
A selective and practical approach for the formation of cis-1,4-aminocyclohexanol was developed. The key transformation involves a one-pot imine formation/ Lewis acid-directed imine reduction and results in a highly selective attack of the reducing agent. This simple and practical method is easily amenable to large-scale synthesis.
Keywords
4-Aminocyclohexanol , reductive amination , Selectivity , cis-1
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1871410
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