Title of article
Design and synthesis of potential new apoptosis agents: hybrid compounds containing perillyl alcohol and new constrained retinoids
Author/Authors
Das، نويسنده , , Bhaskar C. and Mahalingam، نويسنده , , Sakkarapalayam M. and Panda، نويسنده , , Lipsa and Wang، نويسنده , , Bo and Campbell، نويسنده , , Phillp D. and Evans، نويسنده , , Todd، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
5
From page
1462
To page
1466
Abstract
Novel retinoids 1–3 containing perillyl alcohol were synthesized through the addition of perillyl alcohol to the activated carboxylic acids (retinoids) promoted by DCC (N,N′-dicyclohexyl carbodiimide). A set of structurally and functionally diverse perillyl alcohol derivatives of retinoids were obtained in good yields (78–82%). Biological evaluation of these novel hybrid compounds (containing retinoids and perillyl alcohol) is currently underway in our laboratory.
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1871448
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