Title of article
A three-component domino reaction of 2-tetralone, hydroxylamine and acetylene: a one-pot, highly regioselective synthesis of 4,5-dihydrobenz[e]indoles
Author/Authors
Vasil’tsov، نويسنده , , Alexander M. and Ivanov، نويسنده , , Andrei V. and Mikhaleva، نويسنده , , Al’bina I. and Trofimov، نويسنده , , Boris A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
1690
To page
1692
Abstract
2-Tetralone, hydroxylamine and acetylene react in the system MOH/DMSO to give 4,5-dihydrobenz[e]indole and its N-vinyl derivatives in up to 41% and 75% (in the case of excess acetylene) yields, respectively. The amount of the alternative regioisomer, N-vinyl-4,9-dihydrobenz[f]indole, does not exceed 2% (GLC–MS), while the corresponding regioisomer of 4,5-dihydrobenz[e]indole is not detectable.
Keywords
Benzindoles , 2-Tetralone , Acetylene , Domino reaction
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1871578
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