Author/Authors :
Kazakova، نويسنده , , Oxana B. and Tretyakova، نويسنده , , Elena V. and Kukovinets، نويسنده , , Olga S. and Abdrakhmanova، نويسنده , , Albina R. and Kabalnova، نويسنده , , Nataliya N. and Kazakov، نويسنده , , Dmitri V. and Tolstikov، نويسنده , , Genrikh A. and Gubaidullin، نويسنده , , Aidar T.، نويسنده ,
Abstract :
Oxidation of dihydroquinopimaric acid methyl ester and its derivatives with dimethyldioxirane results in the formation of a nontrivial derivative and hemiacetals in high yields with excellent regioselectivity, as is demonstrated for an unsaturated diol. The structures of the products were confirmed by X-ray crystallographic analysis. Dihydroquinopimaric acid and its nontrivial derivative are found to be moderately active against influenza virus type A and the papilloma virus.
Keywords :
Diterpenoids , natural products , Oxidation , Dimethyldioxirane , Quinopimaric acid
