Title of article
An efficient synthesis of 3-(indol-3-yl)quinoxalin-2-ones with TfOH-catalyzed Friedel–Crafts type coupling reaction in air
Author/Authors
Han، نويسنده , , Yanyan and Wu، نويسنده , , Zhijun and Zhang، نويسنده , , Xiao Mei and Yuan، نويسنده , , Wei-Cheng، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
6
From page
2023
To page
2028
Abstract
An efficient one-pot synthetic approach to access a variety of 3-(indol-3-yl)quinoxalin-2-ones from various quinoxalin-2-ones and very wide scope of indoles through TfOH-catalyzed Friedel–Crafts type coupling reaction in DMF has been developed. Only 10 mol % Brønsted acid as a catalyst, air as an oxidizer, and very wide range of substrates are the prominent advantages of this method.
Keywords
3-(Indol-3-yl)quinoxalin-2-ones , Friedel–Crafts reaction , indoles , Trifluoromethanesulfonic acid , Quinoxalin-2-ones
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1871913
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