• Title of article

    Rapid access to morphinones: removal of 4,5-ether bridge with Pd-catalyzed triflate reduction

  • Author/Authors

    Hupp، نويسنده , , Christopher D. and Neumeyer، نويسنده , , John L.، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2010
  • Pages
    3
  • From page
    2359
  • To page
    2361
  • Abstract
    A new synthetic method for the removal of the 4,5-bridged ether moiety of several opioids has been developed. This process offers a faster, simpler synthetic route to obtain the morphinone scaffold in high yields without the need for protection of the ketone moiety.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2010
  • Journal title
    Tetrahedron Letters
  • Record number

    1872083