Title of article
K2PdCl4 catalyzed efficient multicomponent synthesis of α-aminonitriles in aqueous media
Author/Authors
Karmakar، نويسنده , , Bikash and Banerji، نويسنده , , Julie، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
2748
To page
2750
Abstract
An efficient, mild and environmentally friendly method has been developed for the Strecker reaction to synthesize α-aminonitriles in the presence of K2PdCl4 as a catalyst. The three-component one-pot condensation of an aldehyde, amine and trimethylsilyl cyanide proceeded smoothly in water to afford the corresponding product in high yield with short reaction times.
Keywords
Strecker synthesis , multicomponent reaction , water chemistry , K2PdCl4
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1872187
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