Title of article
Synthesis of isoxazolobenzoxepanes via Michael addition of indoles to nitroalkenes and sequential intramolecular nitrile oxide cycloaddition
Author/Authors
Ramachandiran، نويسنده , , K. G. Karthikeyan، نويسنده , , K. and Muralidharan، نويسنده , , D. and Perumal، نويسنده , , P.T.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
3006
To page
3009
Abstract
Nitroalkenes derived from O-propargyl salicylaldehyde undergo facile Michael addition with indoles leading to indole-derived Michael adducts. Intramolecular nitrile oxide cycloaddition (INOC) of the Michael adducts results in isoxazolobenzoxepanes in good to excellent yields.
Keywords
Michael addition , Intramolecular nitrile oxide cycloaddition , Isoxazoles , Benzoxepanes
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1872254
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