Title of article
Efficient catalyst-free Domino approach for the synthesis of novel 2-benzazepine derivatives in water
Author/Authors
Venkata Prasad، نويسنده , , J. and Prabhakar، نويسنده , , Maddela and Manjulatha، نويسنده , , K. and Rambabu، نويسنده , , D. and Anand Solomon، نويسنده , , K. and Gopi Krishna، نويسنده , , G. Sudha Anil Kumar، نويسنده , , K.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
3109
To page
3111
Abstract
A novel one-pot eco-friendly protocol for the synthesis of 2-benzazepine derivatives in water has been developed. 4-Chloro-3-formyl coumarin reacts with benzyl amines under catalyst-free conditions in aqueous medium to afford substituted 5-(2′-hydroxyaryl)-4-amido-2-benzazepines in excellent yields.
Keywords
green chemistry , Benzyl amines , Coumarin , benzazepines , catalyst-free , one-pot synthesis , Scaffold hopping
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1872278
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