Title of article
Efficient synthesis of 1,4-disubstituted polyfunctional piperazines via a sequential one-pot Ugi/nucleophilic addition five-component reaction
Author/Authors
Bararjanian، نويسنده , , Morteza and Balalaie، نويسنده , , Saeed and Movassagh، نويسنده , , Barahman and Bijanzadeh، نويسنده , , Hamid Reza، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
3277
To page
3279
Abstract
Polyfunctional 1,4-disubstituted piperazines were successfully synthesized stereoselectively via a one-pot, five-component Ugi/nucleophilic addition reaction sequence. Regio- and stereo-selective addition of piperazine to an activated alkyne under catalyst-free conditions and high yields of products are advantages of this method.
Keywords
1 , 4-Disubstituted piperazines , Five-component reaction , Active acetylenic compounds , stereoselective synthesis , One-pot Ugi/nucleophilic addition
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1872396
Link To Document