• Title of article

    Enantioselective synthesis of (R)-(+)-α-lipoic acid via proline-catalyzed sequential α-aminoxylation and HWE olefination of aldehyde

  • Author/Authors

    Panchgalle، نويسنده , , Sharad P. and Jogdand، نويسنده , , Ganesh F. and Chavan، نويسنده , , Subhash P. and Kalkote، نويسنده , , Uttam R.، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2010
  • Pages
    3
  • From page
    3587
  • To page
    3589
  • Abstract
    An efficient enantioselective synthesis of (R)-(+)-α-lipoic acid is described, in high optical purity (>97% ee), using l-proline-catalyzed sequential α-aminoxylation and Horner–Wadsworth–Emmons olefination of aldehyde as the key step.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2010
  • Journal title
    Tetrahedron Letters
  • Record number

    1873335