Title of article
Enantioselective synthesis of (R)-(+)-α-lipoic acid via proline-catalyzed sequential α-aminoxylation and HWE olefination of aldehyde
Author/Authors
Panchgalle، نويسنده , , Sharad P. and Jogdand، نويسنده , , Ganesh F. and Chavan، نويسنده , , Subhash P. and Kalkote، نويسنده , , Uttam R.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
3587
To page
3589
Abstract
An efficient enantioselective synthesis of (R)-(+)-α-lipoic acid is described, in high optical purity (>97% ee), using l-proline-catalyzed sequential α-aminoxylation and Horner–Wadsworth–Emmons olefination of aldehyde as the key step.
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1873335
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